Modern management of lymphocyte predominant Hodgkin lymphoma
نویسندگان
چکیده
منابع مشابه
VII. Management of nodular lymphocyte-predominant Hodgkin lymphoma.
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) accounts for about 5% of all Hodgkin lymphoma (HL) cases [1]. This entity differs substantially from the histological subtypes of classical HL (cHL) in terms of immunohistology, clinical presentation, and course. The B-cell marker CD20 that is only inconsistently found on Hodgkin and Reed–Sternberg cells in cHL represents a hallmark of the...
متن کاملXVIII. Management of nodular lymphocyte predominant Hodgkin lymphoma.
Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) represents only ~5% of Hodgkin lymphoma (~1.5 per 1000000 people per year) [1,2].Microscopically, NLPHL displays a nodular growth pattern, although a diffuse growth pattern with prominent histiocytes and T cells can be seen in advanced or recurrent cases. The malignant cells of NLPHL, referred to as LP or ‘popcorn cells’ because of their m...
متن کاملManagement of nodular lymphocyte predominant Hodgkin lymphoma in the modern era.
PURPOSE To analyze treatment outcomes for nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) at a single institution. PATIENTS AND METHODS Patients with newly diagnosed NLPHL between 1996 and 2013 were reviewed retrospectively. Patients treated before 1996 were excluded because the majority received extended field radiation therapy (RT) alone. RESULTS Fifty-five patients (22 ≤ 21 years...
متن کاملTreatment of lymphocyte-predominant Hodgkin lymphoma.
Lymphocyte-predominant Hodgkin lymphoma (LPHL) was first described as Hodgkin’s paragranuloma by Jackson and Parker in 1944 [1]. Subsequently, a number of different terms such as lymphocytic-predominant Hodgkin’s disease or lymphocytic and histiocytic-predominant Hodgkin’s disease were used [2]. LPHL is rare, accounting for 5% of all Hodgkin lymphoma (HL) cases in western countries [3]. LPHL an...
متن کاملHematopathology / NODULAR LYMPHOCYTE PREDOMINANT HODGKIN LYMPHOMA
In our experience, certain commonly cited immunophenotypic features of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) are not encountered in day-to-day practice. We reviewed 60 cases of NLPHL (18 women, 42 men; median age, 34 years) to discern immunophenotypic features from a large, single-institution cohort. All cases contained lymphocytic and histiocytic (L&H) cells. These cells expr...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2013
ISSN: 0007-1048
DOI: 10.1111/bjh.12244